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#1
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So I'm wondering just how severe the side effects are. I only started the bupropion in December and the mirtazapine last week, but I have noticed that before I started either of them, 70F degrees felt very warm to me, and now 70F feels frigid and I can't get warm until I crank the heat to 80, then I suddenly start sweating and feeling like it's the middle of July and I'm standing in Phoenix Arizona.
Additionally, I cannot stop eating constantly. I never seem to feel full anymore, and I just stuff my face with any and all things, as flavors and textures seem to be enhanced and are simply amazing. I've put on several pounds in a week. Are these things normal, and should I be concerned or will the go away as I get used to the medications? |
#2
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Mirtazapine can cause rapid weight gain. It did for me the first time I took it when it was a new med in the 90s. When I took it again a few years later I was reluctant because of that but the pdoc increased the dose and I didn't gain at all. For some reason the higher the dose the less the appetite increase/weight gain and the less the sedation (which is a downside if you want sedation). I seem to remember that I was still able to get to sleep on it though at the higher dose. At 45-60 mg it was pretty much side effect free.
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Bipolar 1, PTSD, GAD, OCD. Clozapine 250 mg, Emsam 12 mg/day patch, topamax 25 mg, ,Gabapentin 1600 mg & 100-2 PRN,. 2.5 mg clonazepam., 75 mg Seroquel and 12.5 mg PRNx2 daily |
#3
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I hated mirtazpine! I was prescribed the brand name (Remeron) a long time ago. It was my first psychiatric med, and I didn't know about the side effects. Also, I was recovering from an eating disorder and in truth needed to gain weight, but not so rapidly and not that way, by never EVER feeling full no matter how much I ate. All I wanted to do on it was eat and sleep. 45 mg was the same as the lower dose for me, no difference.
The result ended up being, I stopped taking it without the pdoc's consent. I don't even know that it helped my depression any as I was so depressed about the rapid weight gain and being sleepy all the time. As a side note, when my cat was recovering from a long-running wasting fungus, the vet prescribed her a medication to improved her appetite. It was a transdermal version of mirtazpine (rubbed on the inside of the outer ear flap). The instructions actually warned to wear gloves while administering lest it absorb into your system. My cat started eating tons on it, and we stopped it once she started getting her weight back up and eating on her own without the med.
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Bipolar 1, PTSD, anorexia, panic disorder, ADHD Seroquel, Cymbalta, propanolol, buspirone, Trazodone, gabapentin, lamotrigine, hydroxyzine, There's a crack in everything. That is how the light gets in. --Leonard Cohen |
#4
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I haven't heard about the temperature regulation side effect, maybe that's something to comment to your doctor about, but I've certainly heard it (mirtazapine) can cause weight gain. I've been taking mirtazapine for years now (10+ years) at either 45 mg or 30 mg and I can safely say it has been a good medicine for me. I take 30 mg right now. It didn't cause weight gain for me but for some it can, and it can be problematic to some people. Bupropion is a medication I'm a little less familiar with, but perhaps the combination of it and mirtazapine will mitigate weight gain? I say that from a complete layperson's perspective, I am no doctor (nor do I plan to be), but I do know a fair amount about these types of medicines because I've been on them for 15+ years. Anyway, I think if it's concerning enough, the temperature regulation thing should be commented to by you to your doctor, and perhaps you could relate the concern for weight gain as well at that consultation? What do you think?
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"Whatever you can do, or dream you can, begin it. Boldness has genius, power, and magic in it!” |
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